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Table 3 Repair of injured rat spinal cord using biomaterial scaffolds and mesenchymal stem cells

From: Repair of injured spinal cord using biomaterial scaffolds and stem cells

Injury SCI Stage Scaffold Outcome Reference
Complete transection (T10) Acute PLGA multichannel conduits Cells integrated well into host tissue [76]
Complete transection (T8-T9) Acute PLGA porous scaffolds and small intestine submucosa Significant improvement in functional outcomes, improved greater axon regeneration [59]
Transection (T10-11) Acute Gelatin sponge Reduced inflammatory response and cavity formation, promotion of angiogenesis [20]
Balloon-induced compression (T8-T9) Implantation of scaffolds with cells 5 weeks after original injury HPMA-RGD hydrogel Significant improvement [58]
  1. HPMA-RGD, N-(2-hydroxypropyl)-methacrylamide with attached amino acid sequence Arg-Gly-Asp; PLGA, poly(lactic-co-glycolic acid).