Figure 5

Cardiac engraftment of periADSCs and the induced vasculogenesis. The prelabeled periADSCs showed a majority of expression eGFP before injection (A, after trypsinization) and optimal cardiac retention (45%; n = 3), but only rare eGFP-positive cells were detected in the heart section (<0.01%; n = 3). Transplantation of periADSCs increased vessel density at the site of injection in comparison with ingADSCs, indicating proangiogenic effects by periADSCs, but did not alter collagen deposition (B, n = 5 and 4). **P < 0.01 and bar = 50 μm in A and 200 μm in B.