Figure 3

Cytokine profile of tumor-derived mesenchymal stromal cells. Tumor-derived mesenchymal stromal cells obtained from three individual patients were cultured for 24 hours and the culture supernatant was harvested. Concentration of cytokines was analyzed with a bead-based multiplex assay. Secretion was classified as no secretion (IL-5, IL-7, IL-10, IL-12, IL-13, IL-17; data not shown), (a) low secretion (<100 pg/ml) and (b) high secretion (>100 pg/ml). Data depicted as mean ± standard deviation. G-CSF, granulocyte colony-stimulating factor; GM-CSF, granulocyte–macrophage colony-stimulating factor; IFN, interferon; IL, interleukin; MIP-1 β, macrophage inflammatory protein-1β; SDF-1α, stromal cell-derived factor-1α; TNFα, tumor necrosis factor alpha; VCAM1, vascular cell adhesion molecule 1.