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Figure 6 | Stem Cell Research & Therapy

Figure 6

From: Influence of insulin-like growth factor I overexpression via recombinant adeno-associated vector gene transfer upon the biological activities and differentiation potential of human bone marrow-derived mesenchymal stem cells

Figure 6

Analyses in osteogenically and adipogenically differentiated cultures of human bone marrow-derived mesenchymal stem cells transduced with rAAV-hIGF-I. Cells in monolayer cultures were transduced with rAAV-hIGF-I or rAAV-lacZ (40 μl each vector) and induced toward osteogenic or adipogenic differentiation as described in Methods. Cultures were processed on day 21 for (A) alkaline phosphatase (ALP) staining with histomorphometry (osteogenesis; magnification × 4) and (B) Oil Red O staining with histomorphometry (adipogenesis; magnification × 10). *Statistically significant compared with rAAV-lacZ. hIGF-I, human insulin-like growth factor I; rAAV, recombinant adeno-associated virus.

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Stem Cell Research & Therapy

ISSN: 1757-6512