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Figure 6 | Stem Cell Research & Therapy

Figure 6

From: Immunomodulatory properties of stem cells from human exfoliated deciduous teeth

Figure 6

SHED transplantation reconstructed trabecular bone and inhibited osteoclast activity. (A) SHED transplantation showed the same effect in regenerating trabecular bone as seen in BMMSC transplanted MRL/lpr mice (n = 6) ([[P < 0.01). (B) TRAP staining showed that the number of TRAP positive osteoclasts was significantly reduced in SHED and BMMSC transplanted mice (n = 6, [P < 0.05). (C, D) ELISA revealed that SHED and BMMSC transplantations were capable of significantly reducing the levels (mean ± SD) of soluble RANKL (sRANKL) (C) and C-terminal telopeptides of type I collagen (CTX) (D) in serum of MRL/lpr mice (n = 6)(*P < 0.05, **P < 0.01).

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