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Table 1 Doubling times of bone marrow stromal cells used for bone formation assessment

From: Pre-clinical studies of bone regeneration with human bone marrow stromal cells and biphasic calcium phosphate

Donor 1 2 3 4 5 6 7 8
Passage 0 doubling time (hours) 20.8 21.5 20.4 21.8 20.2 27.0 27.8 26.4
Passage 1 doubling time (hours) 48.4 35.1 39.7 33.1 34.8 39.6 60.2 39.3
Passage 0 number of population doublings 12.1 11.2 11.7 10.9 11.7 12.4 12.1 12.6
Passage 1 number of population doublings  2.4  3.3  3.0  3.5  3.3  4.2  2.8  4.2
Cumulative population doublings 14.5 14.5 14.7 14.4 15.0 16.6 14.9 16.8
Protocol option as published by Fekete and colleagues [6]  2  2  2  2  2  1  1  1
  1. Donors 1 to 5, ectopic; Donors 6 to 8, calvaria.