Donor | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 |
---|---|---|---|---|---|---|---|---|
Passage 0 doubling time (hours) | 20.8 | 21.5 | 20.4 | 21.8 | 20.2 | 27.0 | 27.8 | 26.4 |
Passage 1 doubling time (hours) | 48.4 | 35.1 | 39.7 | 33.1 | 34.8 | 39.6 | 60.2 | 39.3 |
Passage 0 number of population doublings | 12.1 | 11.2 | 11.7 | 10.9 | 11.7 | 12.4 | 12.1 | 12.6 |
Passage 1 number of population doublings | 2.4 | 3.3 | 3.0 | 3.5 | 3.3 | 4.2 | 2.8 | 4.2 |
Cumulative population doublings | 14.5 | 14.5 | 14.7 | 14.4 | 15.0 | 16.6 | 14.9 | 16.8 |
Protocol option as published by Fekete and colleagues [6] | 2 | 2 | 2 | 2 | 2 | 1 | 1 | 1 |