Skip to main content
Figure 2 | Stem Cell Research & Therapy

Figure 2

From: Human liver stem cells and derived extracellular vesicles improve recovery in a murine model of acute kidney injury

Figure 2

Renal cell proliferation in AKI mice treated with HLSCs. Quantification of BrdU (A) and PCNA (B) positive cells/hpf was performed in renal sections of AKI mice treated with vehicle alone or with different quantities of HLSCs and sacrificed after five days. BrdU was injected intraperitoneally for two consecutive days before mice were killed. Data are expressed as mean ± SD. ANOVA with Dunnet’s multicomparison test was performed: * P <0.05 HLSC-treated AKI mice versus vehicle-treated AKI mice. Representative micrographs of PCNA (C) or BrdU (D) uptake staining performed on sections of kidneys five days after glycerol treatment (two days after vehicle or HLSC injection). Original magnification: ×400. AKI, acute kidney injury; ANOVA, analysis of variance; BrdU, 5-bromo-2′-deoxy-uridine; HLSCs, human liver stem cells; PCNA, proliferating cell nuclear antigen; SD, standard deviation.

Back to article page