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Figure 1 | Stem Cell Research & Therapy

Figure 1

From: 17beta-estradiol promotes the odonto/osteogenic differentiation of stem cells from apical papilla via mitogen-activated protein kinase pathway

Figure 1

Identification of SCAP. (A) Isolated SCAP were stained positively for STRO-1 with typical fibroblast- or spindle-like morphology. (B) PBS served as a negative control. (C) Isolated SCAP were positive for CD73, CD146, CD90 and CD105, but negative for CD45 and CD34 by flow cytometry. (D) In vivo transplantation of SCAP pellets formed the typical dentin-pulp-like complex containing dental pulp, odontoblasts, predentin and dentin. (E) A higher magnification of (D). DP, dental pulp; OB, odontoblast; D, dentin; PD, predentin. Scale bars: A, B and D = 100 μm, E = 25 μm. SCAP, stem cells from apical papilla.

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