Figure 3

microRNA-378 promoted the angiogenesis ability of mesenchymal stem cells. Comparison of the numbers of vascular branches between the two experimental groups in normoxic and hypoxic conditions in vitro. (A) Vascular formation of the different groups in vitro (magnification × 100): (a) native MSCs, MSCs cultured in normoxia conditions; (b) miR-378, miR-378-transfected MSCs cultured in normoxia conditions; (c) MSCs + hypoxia, MSCs cultured in hypoxic conditions; (d) miR-378 + hypoxia, miR-378-transfected MSCs cultured in hypoxic conditions. (B) Comparison of the numbers of vascular branches between groups. **P < 0.01, transfected versus nontransfected MSCs.