Table 4 Pathways for upregulated genes after expansion in serum-free medium (top 10)
Pathway | Gene symbol | Count |
|---|---|---|
Regulation of actin cytoskeleton | ARHGEF6; ARHGEF7; FN1; ITGA10; ITGB8; PDGFD; PIK3R1; PIK3R3; SCIN | 9 |
Mitogen-activated protein kinase signaling pathway | DDIT3; ELK4; IL1R1; MAP2K5; MAP2K6; MAP3K5; MAP3K8; MKNK1; PLA2G12A | 9 |
Systemic lupus erythematosus | C1R; C1S; HIST1H2AC; HIST1H2BC; HIST1H2BD; HIST1H2BK; HIST1H4H | 7 |
Jak-STAT signaling pathway | IL20RB; JAK3; LIFR; PIK3R1; PIK3R3; SPRY1; STAT2 | 7 |
Axon guidance | CXCL12; EPHA4; EPHB6; SRGAP1; SRGAP3; SRGAP2 | 6 |
Focal adhesion | FN1; ITGA10; ITGB8; PDGFD; PIK3R1; PIK3R3 | 6 |
Acute myeloid leukemia | PIK3R1; PIK3R3; PML; RUNX1T1; ZBTB16 | 5 |
Phosphatidylinositol signaling system | IMPA2; PIK3C2A; PIK3C3; PIK3R1; PIK3R3 | 5 |
Apoptosis | CFLAR; IL1R1; IRAK4; PIK3R1; PIK3R3 | 5 |
Toll-like receptor signaling pathway | IRAK4; MAP2K6; MAP3K8; PIK3R1; PIK3R3 | 5 |