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Figure 2 | Stem Cell Research & Therapy

Figure 2

From: Mesenchymal stem cell-mediated suppression of hypertrophic scarring is p53 dependent in a rabbit ear model

Figure 2

Mesenchymal stem cells with or without p53 stable knockdown, both with green fluorescent protein label, were injected via ear artery during the wound healing process of the rabbit ear hypertrophic scar model, and migrated into the scar tissue. (A) Frozen-section analysis and hematoxylin and eosin (HE) staining of scars 4 weeks after model operation. The green fluorescence in the frozen sections indicated the presence of the transplanted mesenchymal stem cells (MSCs) that migrated into the scar tissue. Scale bar, 200 μm. (B) Representative cultured MSCs that were isolated from the scar tissue. Scale bar, 200 μm. Ctrl, control; GFP, green fluorescent protein.

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