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Table 1 Statistical analysis of RNA expression levels comparing groups of different mesenchymal stem cell preparations

From: Relative genomic stability of adipose tissue derived mesenchymal stem cells: analysis of ploidy, H19 long non-coding RNA and p53 activity

 

Mean adipose

Mean BM

Adipose ( n)

BM ( n)

P, Mann–Whitney

P, F-variance

Normoxic adipose vs. BM

      

 H19

0.002

0.092

11

11

0.004

0

 HIF1α

4.786

5.275

11

11

>0.05

0.0007

 VEGFa

2.974

1.647

10

11

0.01

0.01

Hypoxic adipose vs. BM

      

 H19

0.018

0.85

12

6

0.001

0

 HIF1 α

5.157

7.078

12

6

>0.05

0.002

 VEGFa

6.413

3.227

12

6

0.013

>0.05

 

Mean normoxia

Mean hypoxia

Normoxia ( n )

Hypoxia ( n )

P , Mann–Whitney

 

Normoxic vs. hypoxic

      

 H19 BM

0.092

0.85

11

6

0.024

 

 VEGFa BM

1.647

3.227

11

6

0.05

 

 H19 adipose

0.002

0.018

11

12

0.00005

 

 VEGFa adipose

2.974

6.413

10

12

0.00015

 

Diploid vs. polyploid

      

 H19 diploid adipose

0.002

0.018

11

12

  

 H19 polyploid BM

0.099

1.068

10

3

  

 Polyploid BM/diploid adipose

43.137

59.447

    
  1. BM, bone marrow; HIF1α, hypoxia-inducible factor 1α; VEGFa, vascular endothelial growth factor A.