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Figure 4 | Stem Cell Research & Therapy

Figure 4

From: Leukocyte transmigration into tissue-engineered constructs is influenced by endothelial cells through Toll-like receptor signaling

Figure 4

Real-time reverse transcription-polymerase chain reaction (RT-PCR) for mouse-specific genes after 3 weeks of implantation in vivo . Relative gene expression of tumor necrosis factor alpha (TNFα) (A), interleukin-1-beta (IL-1β) (B), IL-6 (C), IL-10 (D), nitric oxide synthase 2 (NOS2) (E), mammalian target of rapamycin (mTOR) (F), hypoxia-inducible factor 1 alpha (HIF-1α) (G), and HIF-1β (H) comparing empty scaffolds with the multipotent stromal cell (MSC) and MSC/endothelial cell (MSC/EC) constructs. Data are presented as mean ± standard deviation (n = 6). *P <0.05; **P <0.01; ***P <0.001. GAPDH, glyceraldehyde 3-phosphate dehydrogenase.

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