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Figure 5 | Stem Cell Research & Therapy

Figure 5

From: Adipose tissue derived stem cells: in vitro and in vivo analysis of a standard and three commercially available cell-assisted lipotransfer techniques

Figure 5

Clinical evaluation. (A, B, C, D) Patient treated with a stem cell-enriched fat grafting technique. (A) Preoperative pictures of the patient after mastectomy and immediate expander reconstruction of the left breast. (B) Ultrasound evaluation image of the preoperative subcutaneous thickness of the mastectomy skin flap over the implant, detected at the level of the median-median quadrant (MMQ). (C) Postoperative pictures at 6 months after the patient underwent expander substitution with an implant and contemporary fat grafting with 230 cm3 stem cell-enriched adipose tissue (Cytori). Shape, volume, and projection of the final implant are good to excellent. (D) Ultrasound evaluation image of the subcutaneous thickness of the mastectomy skin flap at 6 months, detected in the area of the MMQ. (E, F, G, H) Patient treated with the standard fat grafting technique. (E) Preoperative pictures of a patient after mastectomy and immediate expander reconstruction of the right breast. (F) Ultrasound evaluation image of the subcutaneous thickness of the mastectomy skin flap over the implant in the preoperative period, detected at the level of the MMQ. (G) Postoperative pictures at 6 months. Reconstruction was performed with expander substitution with an implant and contemporary fat grafting with 110 cm3 adipose tissue (standard technique). The symmetry is reached, although in the lateral view there is a lack in the right breast projection. (H) Ultrasound evaluation image of the subcutaneous thickness of the mastectomy skin flap at 6 months, detected in the area of the MMQ. (I, J, K, L) Graph boxes showing the subcutaneous thickness gain (mm) in the superior-median quadrant (SMQ) (I, J) and in the MMQ (K, L) at 6 months. (M, N) Graph boxes showing the subcutaneous thickness loss (mm) in the MMQ between 6 and 12 months. Cytori, Cytori Celution System (Cytori Ltd., Deeside, UK) [25]; Fastem, Fastem Corios (CORIOS Soc. Coop, San Giuliano Milanese (MI), Italy); Lipokit, Lipokit Medikhan System (Medikan International Inc, Pusan, Korea) [26].

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