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Figure 3 | Stem Cell Research & Therapy

Figure 3

From: Intra-renal delivery of mesenchymal stem cells attenuates myocardial injury after reversal of hypertension in porcine renovascular disease

Figure 3

MSC decreased inflammation. A) Renal release of interleukin (IL)1α, IL1rα, IL1β, IL10, e-selectin, and endothelin (ET)-1 in study groups. B) Immunostaining for CD68/iNOS (M1) and CD68/Arginase-1 (M2) macrophages (top), their quantification and ratio (bottom). C) Representative immunoblots and myocardial protein expression of IL10 in normal, RVH, RVH + PTRA, and RVH + PTRA + MSC pigs. *P <0.05 versus normal, †P <0.05 versus RVH + PTRA + MSC. MSC, mesenchymal stem cells; PTRA, percutaneous transluminal renal angioplasty; RVH, renovascular hypertension.

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Stem Cell Research & Therapy

ISSN: 1757-6512