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Figure 3 | Stem Cell Research & Therapy

Figure 3

From: Reductions in behavioral deficits and neuropathology in the R6/2 mouse model of Huntington’s disease following transplantation of bone-marrow-derived mesenchymal stem cells is dependent on passage number

Figure 3

Assessment of motor coordination in R6/2 mice following bone marrow mesenchymal stem cell transplantation. A significant decline in motor coordination was observed in untreated R6/2 mice when compared with wild-type (WT) mice. The R6/2 mice who received transplantation of high-passage bone marrow mesenchymal stem cells (BM MSCs) displayed significantly longer latencies to fall compared with untreated R6/2 mice starting at 7 weeks of age and continuing throughout the study. *Significant from WT; #significant from R6/2; †significant from high-passage BM MSCs. Data points on line graph represent mean value; error bars represent standard error of the mean.

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Stem Cell Research & Therapy

ISSN: 1757-6512