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Figure 5 | Stem Cell Research & Therapy

Figure 5

From: Reductions in behavioral deficits and neuropathology in the R6/2 mouse model of Huntington’s disease following transplantation of bone-marrow-derived mesenchymal stem cells is dependent on passage number

Figure 5

Limb-clasping response of R6/2 mice following bone marrow mesenchymal stem cell transplantation. Untreated R6/2 mice had significantly more limb-clasping responses than wild-type (WT) mice starting at 8 weeks of age, with this impairment continuing for the duration of the study. R6/2 mice that received transplantations of high-passage bone marrow mesenchymal stem cells (BM MSCs) had significantly fewer limb-clasping responses than untreated R6/2 mice for the duration of the study, starting at 9 weeks of age. *Significant from WT; #significant from R6/2; †significant from high-passage BM MSCs. Data points on line graph represent mean value; error bars represent standard error of the mean.

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Stem Cell Research & Therapy

ISSN: 1757-6512