Reductions in behavioral deficits and neuropathology in the R6/2 mouse model of Huntington’s disease following transplantation of bone-marrow-derived mesenchymal stem cells is dependent on passage number

Table 2 Flow cytometry results of low-passage and high-passage bone marrow mesenchymal stem cells

An increase in the number of cells positively expressing SCA1 was observed as the passage number increased. An increase in the stem cell marker SSEA4 was also observed as the cell passage increased. Expression levels of CD45, MHC class I, and MHC class II remained relatively stable as the passage number increased. MHC, major histocompatibility complex.

ISSN: 1757-6512