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Table 2 Molecular functions of upregulated genesa

From: Gene expression changes with differentiation of cord blood stem cells to respiratory epithelial cells: a preliminary observation

Molecular function

MLPCs (induced)

Genome

Transcription regulation

15.4

10.4

Hydrolase

10.4

8.7

Unknown function

10.4

 

RNA binding

9.9

 

Protein binding

9.2

 

DNA binding

6.2

9.1

Transport

4.9

5.9

Signaling

4.9

21.1

Oxidoreductase

4.3

3.8

Receptor

4.3

4.7

Kinase

3.7

1.1

Transferase

3.1

8.2

Chaperone

2.5

 

Ion transport

2.5

1.9

Ligase

1.9

 

Developmental

1.2

2.8

Membrane protein

1.2

 

Protein synthesis

1.2

 

Metal binding

0.6

6.2

Nuclear anchor

0.6

 

Immune modulation

0.6

 

Protease inhibitor

0.6

 
  1. aMLPC, multilineage progenitor cell. Molecular functions of genes upregulated in small airway growth medium-induced cells, as defined in the Swiss-Prot and TrEMBL databases, expressed as a percentage of the total upregulated group and compared to molecular functions of all known genes in the genome (see Wade et al. [8]).