Official symbol | Name | Fold change | Significance |
---|---|---|---|
ALDH3A1 | Aldehyde dehydrogenase 3 family member A1 | 13.2 | Expressed in rat lung and non-small cell lung cancers. May contribute to cyclophosphamide resistance. |
FDXR | Ferredoxin reductase | 9.8 | Higher expression levels seen in metastatic colorectal cancer than in normal controls. |
GADD45B | Growth arrest and DNA damage-inducible β | 7.6 | Induced by differentiation-inducing cytokines. |
SGK1 | Serum/glucocorticoid-regulated kinase 1 | 5.0 | Expressed in lung, functioning in water and sodium balance. Mineralocorticoid-responsive. |
VDR | Vitamin D (1,25-dihydroxyvitamin D3) receptor | 4.6 | Hypothesized to play a key role in ATII maturation and surfactant synthesis. |
HSP90B1 | Heat shock protein 90 kDa β (Grp94) | 4.2 | Increased expression seen in mesothelioma and squamous cell lung cancer. |
HDS17B1 | Hydroxysteroid (17β) dehydrogenase 11 | 3.6 | Expressed in distal bronchioles and ATII cells. |
CHKA | Choline kinase α | 3.4 | Expressed in adult rat ATII cells. Forms part of synthesis pathway for phosphatidylcholine (pulmonary surfactant synthesis). |