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Table 6 Hormone-responsive and additional genes of interest: GeneChip and real-time PCR dataa

From: Gene expression changes with differentiation of cord blood stem cells to respiratory epithelial cells: a preliminary observation

Official symbol

Name

qRT-PCR I/C

GeneChip I/C

Significance

SBP

Surfactant protein B

NA

-0.6

Putative HR gene

LAMP3

Lysosomal associated membrane protein 3

0.03

1.0

HR

LPL

Lipoprotein lipase

1.43

25.0

HR

SERPINA1

α1 antiproteinase, antitrypsin

1.7

15.0

Secreted by ATII cells; functional importance

ABCA3

ATP-binding cassette, subfamily A, member 3

7.9

100.0

Expressed in lung; functions in surfactant production

HIF3a

Hypoxia-inducible factor 3, α-subunit

7.9

60.0

HR

MAOA

Monoamine oxidase A

10.0

25.0

HR

ABCA1

ATP-binding cassette, subfamily A, member 1

103.2

6.0

Expressed in lung; functions in surfactant production

NR4A2

Nuclear receptor subfamily 4, group A, member 2

110.7

5.0

HR

ALDH1b

Aldehyde dehydrogenase 1β

10,716.0

2.0

HR

GAPDH

Glyceraldehyde 3-phosphate dehydrogenase

1.1

NA

Housekeeping gene

  1. aPCR, polymerase chain reaction; qRT-PCR, quantitative real-time polymerase chain reaction; I/C, ratio of induced to control cells; HR, hormone-responsive; ATII, alveolar type II pneumocyte; NA, not applicable. GeneChip and quantitative PCR data are expressed as ratios of induced to control cells and the context (that is, significance) of this gene.