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Figure 2 | Stem Cell Research & Therapy

Figure 2

From: Amnion-derived stem cells: in quest of clinical applications

Figure 2

Illustration of 'stem cell left behind' theory. At 8 days after fertilization, inner cell mass differentiates into epiblast and hypoblast. An amniotic cavity appears in the middle of the epiblast. As the cavity grows, the spatial segregation allows some amnioblasts to retain epiblast-like stem cells. Red stars indicate an amniotic cavity, and pink arrows indicate short-range organogenic signals that could not reach the amnioblasts.

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