Figure 1

Human induced pluripotent stem cells can be differentiated into cell types to study neurological disorders. Human induced pluripotent (iPS) stem cells can be differentiated into cell types relevant for the study of neurological disorders. Somatic cells from patients with neurological disorders can be reprogrammed into pluripotent stem cells, which in turn can be differentiated into distinct neuronal and glial cell types, thus offering a human cell platform for mechanistic studies and high-throughput screening for diseases of the central and peripheral nervous system.