Table 1 Effects on differentiation potential of multipotent/pluripotent stem cells after treatment with epigenetic drugs
Stem cell classification | Epigenetic drug | Differentiation after treatment | Reference |
|---|---|---|---|
Multipotent stem cells | Â | Â | Â |
   Adipose-derived stem cells | 5-aza-2'-deoxycytidine | Cardiomyocytes | [38] |
   Adipose-derived stem cells | 5-aza-2'-deoxycytidine; trichostatin A | Cardiomyocytes | [57] |
   Bone marrow mesenchymal stem cells | 5-aza-2'-deoxycytidine | Osteocytes | |
   Bone marrow mesenchymal stem cells | 5-aza-2'-deoxycytidine | Cardiomyocytes | |
   Bone marrow mesenchymal stem cells | 5-aza-2'-deoxycytidine; trichostatin A | Osteocytes; chondrocytes | [41] |
   Bone marrow mesenchymal stem cells | 5-aza-2'-deoxycytidine; trichostatin A | Neural-like cells | [42] |
   Bone marrow mesenchymal stem cells | Sodium butyrate | Osteocytes | [59] |
   Cardiac progenitor stem cells | 5-aza-2'-deoxycytidine | Cardiomyocytes | [60] |
   Neural progenitor stem cells | Trichostatin A | Neuronal cells | [61] |
   Neural progenitor stem cells | Valproic acid | Neuronal cells | [62] |
   Umbilical cord mesenchymal stem cells | 5-aza-2'-deoxycytidine | Cardiomyocytes | [63] |
Pluripotent stem cells | Â | Â | Â |
   Embryonic stem cells | 5-aza-2'-deoxycytidine | Cardiomyocytes | |
   Embryonic stem cells | 5-aza-2'-deoxycytidine | Endothelial cells | [66] |
   Embryonic stem cells | Trichostatin A | Cardiomyocytes |