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Figure 5 | Stem Cell Research & Therapy

Figure 5

From: Successful disease-specific induced pluripotent stem cell generation from patients with kidney transplantation

Figure 5

Sequence analysis confirms PKD1 mutation in autosomal-dominant polycystic kidney disease-specific induced pluripotent stem cells. Autosomal-dominant polycystic kidney disease (ADPKD) patient DNA and ADPKD- induced pluripotent stem (iPS) cell DNA were analyzed by sequencing analysis. Sequence of exon 41 of PKD1 showing the 11,525G > A change resulting in W3842X in the ADPKD-iPS cells (center) and the patient's germline DNA (top) but not in the Wilms tumor (WT)-iPS cells (bottom).

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Stem Cell Research & Therapy

ISSN: 1757-6512