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Table 1 Clinical features of experimental autoimmune encephalomyelitis-affected mice

From: The therapeutic effect of mesenchymal stem cell transplantation in experimental autoimmune encephalomyelitis is mediated by peripheral and central mechanisms

 

Disease incidence

Disease onset, days after immunization

Mean maximum neurologic score

Cumulative disease score

EAE control i.v.

14/14 (100%)

12 ± 0.8

3 ± 0.5

84.4 ± 13

EAE + MSCs i.v.

14/15 (93.4%)

11.5 ± 0.5

2.5 ± 0.9

67.6 ± 28.7*

EAE control i.t.

14/14 (100%)

11.6 ± 0.6

3 ± 0.5

85.2 ± 15.3

EAE + MSCs i.t.

14/15 (93.4%)

12.3 ± 1

2.4 ± 0.7*

63.7 ± 25.7*

  1. Data presented as n /total (%) or mean ± standard deviation. EAE, experimental autoimmune encephalomyelitis; i.t., intrathecally; i.v., intravenously; MSC, mesenchymal stem cell. *P ≤0.05 (Student's t test).
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Stem Cell Research & Therapy

ISSN: 1757-6512