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  1. The role of brown fat in non-shivering thermogenesis and the discovery of brown fat depots in adult humans has made it the subject of intense research interest. A renewable source of brown adipocyte (BA) proge...

    Authors: Michael D. West, Ching-Fang Chang, Dana Larocca, Jie Li, Jianjie Jiang, Pamela Sim, Ivan Labat, Karen B. Chapman, Kari E. Wong, James Nicoll, Michael J. Van Kanegan, Aubrey D. N. J. de Grey, Igor O. Nasonkin, Andreas Stahl and Hal Sternberg
    Citation: Stem Cell Research & Therapy 2019 10:7
  2. The original article [1] contained errors in the presentation of Figure 7.

    Authors: Lian Ru Gao, Ning Kun Zhang, Yan Zhang, Yu Chen, Li Wang, Ying Zhu and Hai Hong Tang
    Citation: Stem Cell Research & Therapy 2019 10:6

    The original article was published in Stem Cell Research & Therapy 2018 9:339

  3. The etiology and pathology osteonecrosis of the femoral head (ONFH) are not completely clarified. As a cytokine participating in systemic inflammation, tumor necrosis factor alpha (TNFα) has been shown to be i...

    Authors: Bin Fang, Ding Wang, Jiaqian Zheng, Qiushi Wei, Dongxiang Zhan, Yamei Liu, Xuesong Yang, Haibin Wang, Gang Li, Wei He and Liangliang Xu
    Citation: Stem Cell Research & Therapy 2019 10:5
  4. To explore the effect of mesenchymal stem cells isolated from menstrual blood (MB-MSCs) on epirubicin-induced damage to human ovarian granulosa cells (GCs) and its potential mechanisms.

    Authors: Zhongrui Yan, Fengyi Guo, Qing Yuan, Yu Shao, Yedan Zhang, Huiyan Wang, Shaohua Hao and Xue Du
    Citation: Stem Cell Research & Therapy 2019 10:4
  5. Hertwig’s epithelial root sheath (HERS) is important in guiding tooth root formation by differentiating into cementoblasts through epithelial–mesenchymal transition (EMT) and inducing odontoblastic differentia...

    Authors: Xuebing Li, Sicheng Zhang, Zirui Zhang, Weihua Guo, Guoqing Chen and Weidong Tian
    Citation: Stem Cell Research & Therapy 2019 10:3
  6. Tendon stem/progenitor cells (TSPC) exhibit a low proliferative response to heal tendon injury, leading to limited regeneration outcomes. Exogenous growth factors that activate TSPC proliferation have emerged ...

    Authors: Tsung-Chuan Ho, Shawn H. Tsai, Shu-I Yeh, Show-Li Chen, Kwang-Yi Tung, Hsin-Yu Chien, Yung-Chang Lu, Chang-Hung Huang and Yeou-Ping Tsao
    Citation: Stem Cell Research & Therapy 2019 10:2
  7. Heart failure has become a global health problem with increasing incidences worldwide. Traditional pharmacological treatments can delay but cannot reverse the underlying disease processes. The clinical applica...

    Authors: Fei Zhang, Yuan Xie and Yuhao Bian
    Citation: Stem Cell Research & Therapy 2018 9:358
  8. Methotrexate (MTX) is widely used for the treatment of rheumatoid arthritis (RA). The drug is cost-effective, but sometimes causes hepatotoxicity, requiring a physician’s attention. In this study, we simulated...

    Authors: Juryun Kim, Yena Kim, Jinhyeok Choi, Hyerin Jung, Kijun Lee, Jaewoo Kang, Narae Park, Yeri Alice Rim, Yoojun Nam and Ji Hyeon Ju
    Citation: Stem Cell Research & Therapy 2018 9:357
  9. Bone marrow mesenchymal stem cells (BMSCs) can provide an additional source of therapeutic stem cells for regeneration of liver cells during acute liver injury (ALI). However, the insufficient hepatic homing b...

    Authors: Ting Sun, Feng Gao, Xin Li, Yingyu Cai, Min Bai, Fan Li and Lianfang Du
    Citation: Stem Cell Research & Therapy 2018 9:356
  10. Human embryonic stem cells (hESC) and induced pluripotent stem cells (hiPSC) are considered attractive sources of pancreatic β cells and islet organoids. Recently, several reports presented that hESC/iPSC-deri...

    Authors: Hussain Md. Shahjalal, Ahmed Abdal Dayem, Kyung Min Lim, Tak-il Jeon and Ssang-Goo Cho
    Citation: Stem Cell Research & Therapy 2018 9:355
  11. This article [1] has been retracted by the authors because, contrary to the statement in the article, ethical approval was not obtained to conduct this study.

    Authors: Ihn Han, Miyong Yun, Eun-Ok Kim, Bonglee Kim, Min-Hyung Jung and Sung-Hoon Kim
    Citation: Stem Cell Research & Therapy 2018 9:354

    The original article was published in Stem Cell Research & Therapy 2014 5:54

  12. A 27-year-old male with HIV-associated naïve and high-risk Burkitt’s lymphoma sequentially received short-term, high-dose non-myeloablative chemotherapy and autologous CD34-positive stem cell transfusion in th...

    Authors: Haiyan Min, Jianwei Yang, Sanbin Wang, Pengfei Tao, Yuqin Song, Xiaopei Wang, Huiqin Li, Xinping Yang, Xingqi Dong, Fu-Sheng Wang, Ming Shi, Xicheng Wang and Ruonan Xu
    Citation: Stem Cell Research & Therapy 2018 9:353
  13. Adipose tissue is an excellent source for isolation of stem cells for treating various clinical conditions including injuries to the neuromuscular system. Many previous studies have focused on differentiating ...

    Authors: R. El-Habta, M. Sloniecka, P. J. Kingham and L. J. Backman
    Citation: Stem Cell Research & Therapy 2018 9:352
  14. Human bone marrow-derived mesenchymal stem/stromal cells (hBM MSCs) have multiple functions, critical for skeletal formation and function. Their functional heterogeneity, however, represents a major challenge ...

    Authors: Alison T. Merryweather-Clarke, David Cook, Barbara Joo Lara, Peng Hua, Emmanouela Repapi, Neil Ashley, Shiang Y. Lim and Suzanne M. Watt
    Citation: Stem Cell Research & Therapy 2018 9:351
  15. Ischemic vascular diseases are the major cause of death worldwide. In recent years, endothelial cell (EC)-based approaches to vascular regeneration are increasingly viable strategies for treating ischemic dise...

    Authors: Fuyi Cheng, Yujing Zhang, Yuan Wang, Qingyuan Jiang, Cheng jian Zhao, Jie Deng, Xiaolei Chen, Yunqi Yao, Zhemin Xia, Lin Cheng, Lei Dai, Gang Shi, Yang Yang, Shuang Zhang, Dechao Yu, Yuquan Wei…
    Citation: Stem Cell Research & Therapy 2018 9:350
  16. The discovery of animal cloning and subsequent development of cell reprogramming technology were quantum leaps as they led to the achievement of rejuvenation by cell reprogramming and the emerging view that ag...

    Authors: Rodolfo G. Goya, Marianne Lehmann, Priscila Chiavellini, Martina Canatelli-Mallat, Claudia B. Hereñú and Oscar A. Brown
    Citation: Stem Cell Research & Therapy 2018 9:349
  17. This study was aimed to investigate the role and specific molecular mechanism of HIF1A-AS2/miR-665/IL6 axis in regulating osteogenic differentiation of adipose-derived stem cells (ASCs) via the PI3K/Akt signal...

    Authors: Ruoyu Wu, Jihao Ruan, Yongjin Sun, Mengyu Liu, Zhuang Sha, Cunyi Fan and Qingkai Wu
    Citation: Stem Cell Research & Therapy 2018 9:348
  18. Millions of people are affected with retinal diseases that eventually cause blindness, and retinal progenitor cell (RPC) transplantation is a promising therapeutic avenue. However, RPC expansion and the underl...

    Authors: Caixia Jin, Qingjian Ou, Zongyi Li, Juan Wang, Jieping Zhang, Haibin Tian, Jing-Ying Xu, Furong Gao, Lixia Lu and Guo-Tong Xu
    Citation: Stem Cell Research & Therapy 2018 9:346
  19. Basic fibroblast growth factor (bFGF) regulates maintenance of stemness and modulation of osteo/odontogenic differentiation and mineralization in stem cells from human exfoliated deciduous teeth (SHEDs). Miner...

    Authors: Nunthawan Nowwarote, Waleerat Sukarawan, Prasit Pavasant, Brian L. Foster and Thanaphum Osathanon
    Citation: Stem Cell Research & Therapy 2018 9:345
  20. Renal ischemia–reperfusion (I/R) injury is a major cause of acute kidney injury (AKI), which is associated with high morbidity and mortality. AKI is a serious and costly medical condition. Effective therapy fo...

    Authors: Wen-Ching Shen, Yu-Hsiang Chou, Hsiang-Po Huang, Jenn-Feng Sheen, Shih-Chieh Hung and Hsin-Fu Chen
    Citation: Stem Cell Research & Therapy 2018 9:344
  21. Bone marrow-derived mesenchymal stem cells (BMSCs) are gradually getting attention because of its multi-directional differentiation potential, hematopoietic support, and promotion of stem cell implantation. Ho...

    Authors: Lihong Wang, Xianjing Han, Guojing Qu, Le Su, Baoxiang Zhao and Junying Miao
    Citation: Stem Cell Research & Therapy 2018 9:343
  22. Three-dimensional (3D) floating culture clumps of mesenchymal stem cell (MSC)/extracellular matrix (ECM) complexes (C-MSCs) consist of cells and self-produced ECM. Previous studies have demonstrated that C-MSC...

    Authors: Nao Komatsu, Mikihito Kajiya, Souta Motoike, Manabu Takewaki, Susumu Horikoshi, Tomoyuki Iwata, Kazuhisa Ouhara, Katsuhiro Takeda, Shinji Matsuda, Tsuyoshi Fujita and Hidemi Kurihara
    Citation: Stem Cell Research & Therapy 2018 9:342
  23. During differentiation of stem cells, it is recognized that molecular mechanisms of transcription factors manage stem cells towards the intended lineage. In this study, using microarray-based technology, gene ...

    Authors: Se Won Yi, Hye Jin Kim, Hyun Jyung Oh, Heejun Shin, Jung Sun Lee, Ji Sun Park and Keun-Hong Park
    Citation: Stem Cell Research & Therapy 2018 9:341
  24. Despite considerable progress in the development of methods for hematopoietic differentiation, efficient generation of transplantable hematopoietic stem cells (HSCs) and other genuine functional blood cells fr...

    Authors: Mengge Wang, Hongtao Wang, Yuqi Wen, Xiaoyuan Chen, Xin Liu, Jie Gao, Pei Su, Yuanfu Xu, Wen Zhou, Lihong Shi and Jiaxi Zhou
    Citation: Stem Cell Research & Therapy 2018 9:340

    The Correction to this article has been published in Stem Cell Research & Therapy 2020 11:446

  25. Apelin plays a key beneficial role in energy metabolism by increasing glucose uptake and insulin sensitivity; however, apelin has a short half-life because it is rapidly cleared from the circulation limiting i...

    Authors: Lian Ru Gao, Ning Kun Zhang, Yan Zhang, Yu Chen, Li Wang, Ying Zhu and Hai Hong Tang
    Citation: Stem Cell Research & Therapy 2018 9:339

    The Correction to this article has been published in Stem Cell Research & Therapy 2019 10:6

  26. The Wnt/β-catenin signaling pathway plays an important role in the development of second heart field (SHF Isl1+) that gives rise to the anterior heart field (AHF) cardiac progenitor cells (CPCs) for the format...

    Authors: Yong Fan, Beatrice Xuan Ho, Jeremy Kah Sheng Pang, Nicole Min Qian Pek, Jin Hui Hor, Shi-Yan Ng and Boon-Seng Soh
    Citation: Stem Cell Research & Therapy 2018 9:338
  27. As the implantation and long-term existence of tumor-specific T cells in host are the prerequisite for adoptive immunotherapy, memory stem T cells (TSCM) with self-renewal and differentiation capacity show the gr...

    Authors: Liping Guan, Xiaoyi Li, Jiali Wei, Zhihui Liang, Jing Yang, Xiufang Weng and Xiongwen Wu
    Citation: Stem Cell Research & Therapy 2018 9:337
  28. Mesenchymal stem cells (MSC) comprise a heterogeneous population of rapidly proliferating cells that can be isolated from adult (e.g., bone marrow, adipose tissue) as well as fetal (e.g., umbilical cord) tissu...

    Authors: Ioannis Christodoulou, Maria Goulielmaki, Marina Devetzi, Mihalis Panagiotidis, Georgios Koliakos and Vassilis Zoumpourlis
    Citation: Stem Cell Research & Therapy 2018 9:336
  29. Silicosis is a common occupational disease, characterized by silicotic nodules and diffuse pulmonary fibrosis. We demonstrated an anti-fibrotic effect of bone marrow mesenchymal stem cells (BMSCs) in silica-in...

    Authors: Xiaoli Li, Guoliang An, Yan Wang, Di Liang, Zhonghui Zhu and Lin Tian
    Citation: Stem Cell Research & Therapy 2018 9:335
  30. Stem cells from apical papilla (SCAP) are a subpopulation of mesenchymal stem cells (MSCs) isolated from the apical papilla of the developing tooth root apex of human teeth. Because of their osteogenic/dentino...

    Authors: Yosuke Tanaka, Soichiro Sonoda, Haruyoshi Yamaza, Sara Murata, Kento Nishida, Shion Hama, Yukari Kyumoto-Nakamura, Norihisa Uehara, Kazuaki Nonaka, Toshio Kukita and Takayoshi Yamaza
    Citation: Stem Cell Research & Therapy 2018 9:334
  31. Cell-based regenerative medicine therapies are now frequently tested in clinical trials. In many conditions, cell therapies are administered systemically, but there is little understanding of their fate, and a...

    Authors: Lauren Scarfe, Arthur Taylor, Jack Sharkey, Rachel Harwood, Michael Barrow, Joan Comenge, Lydia Beeken, Cai Astley, Ilaria Santeramo, Claire Hutchinson, Lorenzo Ressel, Jon Smythe, Eric Austin, Raphael Levy, Matthew J. Rosseinsky, Dave J. Adams…
    Citation: Stem Cell Research & Therapy 2018 9:332
  32. Bone tissue engineering is not widely used in clinical treatment. Two main reasons hide behind this: (1) the seed cells are difficult to obtain and (2) the process of tissue engineering bone construction is to...

    Authors: Dingyu Wu, Zhenxing Wang, Jinbing Wang, Yingnan Geng, Zhanzhao Zhang, Yu Li, Qiannan Li, Zhiwei Zheng, Yilin Cao and Zhi-Yong Zhang
    Citation: Stem Cell Research & Therapy 2018 9:331
  33. Menstrual blood-derived endometrial stem cells (MenSCs) emerge as an ideal source for cell-based treatment in regenerative medicine and immunotherapy. However, the major obstacle is the low survival rate in ti...

    Authors: Jiang Du, Xinxing Zhu, Rui Guo, Zhihao Xu, Fang Fang Cheng, Qing Liu, Fen Yang, Lihong Guan, Yanli Liu and Juntang Lin
    Citation: Stem Cell Research & Therapy 2018 9:330
  34. Mesenchymal stem cells (MSCs) are found in synovial fluid (SF) and can easily be harvested during arthrocentesis or arthroscopy. However, SF-MSC characterization and chondrogenicity in collagen sponges have be...

    Authors: Paul Neybecker, Christel Henrionnet, Elise Pape, Didier Mainard, Laurent Galois, Damien Loeuille, Pierre Gillet and Astrid Pinzano
    Citation: Stem Cell Research & Therapy 2018 9:329
  35. The tissue engineering of urinary bladder advances rapidly reflecting clinical need for a new kind of therapeutic solution for patients requiring urinary bladder replacement. Majority of the bladder augmentati...

    Authors: Marta Pokrywczynska, Arkadiusz Jundzill, Marta Rasmus, Jan Adamowicz, Daria Balcerczyk, Monika Buhl, Karolina Warda, Lukasz Buchholz, Maciej Gagat, Dariusz Grzanka and Tomasz Drewa
    Citation: Stem Cell Research & Therapy 2018 9:328
  36. Lung cancer stem cells have the ability to self-renew and are resistant to conventional chemotherapy. MicroRNAs (miRNAs) regulate and control the expression and function of many target genes; therefore, miRNA ...

    Authors: Xiaoyuan Wang, Qingwei Meng, Wenbo Qiao, Ruishuang Ma, Weiwei Ju, Jing Hu, Hailing Lu, Jianqi Cui, Zhao Jin, Yanbin Zhao and Yan Wang
    Citation: Stem Cell Research & Therapy 2018 9:327
  37. Human umbilical cord blood-derived mesenchymal stem cells (hUCB-MSCs) have been shown to prevent brain damage and improve neurocognition following intraventricular hemorrhage (IVH). However, the molecular mech...

    Authors: Hyo Rim Ko, So Yoon Ahn, Yun Sil Chang, Inwoo Hwang, Taegwan Yun, Dong Kyung Sung, Se In Sung, Won Soon Park and Jee-Yin Ahn
    Citation: Stem Cell Research & Therapy 2018 9:326
  38. The use of secretome may be a new strand of cell therapy, which is equal to or even superior to the injection of live cells, called cell-free therapy. In ovarian transplantation, this approach may be a therape...

    Authors: Luciana Lamarão Damous, Ana Elisa Teófilo Saturi de Carvalho, Juliana Sanajotti Nakamuta, Marcos Eiji Shiroma, Andressa Cristina Sposato Louzada, José Maria Soares-Jr, José Eduardo Krieger and Edmund C. Baracat
    Citation: Stem Cell Research & Therapy 2018 9:323
  39. Early-stage diabetic retinopathy (DR) is characterized by neurovascular defects. In this study, we hypothesized that human adipose-derived stem cells (ASCs) positive for the pericyte marker CD140b, or their se...

    Authors: Sally L. Elshaer, William Evans, Mickey Pentecost, Raji Lenin, Ramesh Periasamy, Kumar Abhiram Jha, Shanta Alli, Jordy Gentry, Samuel M. Thomas, Nicolas Sohl and Rajashekhar Gangaraju
    Citation: Stem Cell Research & Therapy 2018 9:322
  40. Hepatocyte transplantation has been proposed as an effective treatment for patients with acute liver failure (ALF), but its application is limited by a severe shortage of donor livers. Human pluripotent stem c...

    Authors: Quan-Wen Liu, Qian-Yu Liu, Jing-Yuan Li, Li Wei, Kang-Kang Ren, Xiang-Cheng Zhang, Ting Ding, Ling Xiao, Wen-Jie Zhang, Han-You Wu and Hong-Bo Xin
    Citation: Stem Cell Research & Therapy 2018 9:321
  41. Mesenchymal stem cells (MSCs) are adult stromal cells with the capacity to differentiate into multiple types of cells. MSCs represent an attractive option in regenerative medicine due to their multifaceted abi...

    Authors: Guanguan Qiu, Guoping Zheng, Menghua Ge, Jiangmei Wang, Ruoqiong Huang, Qiang Shu and Jianguo Xu
    Citation: Stem Cell Research & Therapy 2018 9:320
  42. Better understanding of the signaling pathways that regulate human bone marrow stromal stem cell (hBMSC) differentiation into bone-forming osteoblasts is crucial for their clinical use in regenerative medicine...

    Authors: Nihal AlMuraikhi, Dalia Ali, Aliah Alshanwani, Radhakrishnan Vishnubalaji, Muthurangan Manikandan, Muhammad Atteya, Abdulaziz Siyal, Musaad Alfayez, Abdullah Aldahmash, Moustapha Kassem and Nehad M. Alajez
    Citation: Stem Cell Research & Therapy 2018 9:319
  43. Developing cartilage constructed with the appropriate matrix composition and persistent chondrogenesis remains an enduring challenge in cartilage defects. Cartilage progenitor cell (CPC)-based tissue engineeri...

    Authors: Yahong Chen, Ke Xue, Xiaodie Zhang, Zhiwei Zheng and Kai Liu
    Citation: Stem Cell Research & Therapy 2018 9:318
  44. Spermatogonial stem cell transplantation (SSCT) could become a fertility restoration tool for childhood cancer survivors. However, since in mice, the colonization efficiency of transplanted spermatogonial stem...

    Authors: Prashant Kadam, Elissavet Ntemou, Yoni Baert, Sven Van Laere, Dorien Van Saen and Ellen Goossens
    Citation: Stem Cell Research & Therapy 2018 9:317
  45. Human muscle-derived stem cells (hMDSCs) have been shown to regenerate bone efficiently when they were transduced with Lenti-viral bone morphogenetic protein 2 (LBMP2). However, whether the age of hMDSCs and t...

    Authors: Xueqin Gao, Aiping Lu, Ying Tang, Johannes Schneppendahl, Andrea B. Liebowitz, Alex C. Scibetta, Elizabeth R. Morris, Haizi Cheng, Charles Huard, Sarah Amra, Bing Wang, Mary A. Hall, Walter R. Lowe and Johnny Huard
    Citation: Stem Cell Research & Therapy 2018 9:316

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