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  1. An amendment to this paper has been published and can be accessed via the original article.

    Authors: Hongtao Wang, Mengge Wang, Yu Wang, Yuqi Wen, Xiaoyuan Chen, Dan Wu, Pei Su, Wen Zhou, Lihong Shi and Jiaxi Zhou

    Citation: Stem Cell Research & Therapy 2020 11:242

    Content type: Correction

    Published on:

    The original article was published in Stem Cell Research & Therapy 2020 11:147

  2. Mesenchymal stem cells (MSCs) have become a promising candidate for cell-based immune therapy for acute rejection (AR) after heart transplantation due to possessing immunomodulatory properties. In this study, ...

    Authors: Chao Gao, Xiaodong Wang, Jian Lu, Zhilin Li, Haowen Jia, Minghao Chen, Yuchen Chang, Yanhong Liu, Peiyuan Li, Baotong Zhang, Xuezhi Du and Feng Qi

    Citation: Stem Cell Research & Therapy 2020 11:241

    Content type: Research

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  3. Many studies have shown that long noncoding RNAs (lncRNAs) are closely related to the stimulation of osteogenic differentiation of adipose-derived stem cells (ADSCs) and the prevention of osteoporosis. Current...

    Authors: Zheng-liang Shi, Hua Zhang, Zhi-yong Fan, Wei Ma, Yong-zhou Song, Ming Li, Tong-qiu Li, Shu-xing Cao and Guo-jun Feng

    Citation: Stem Cell Research & Therapy 2020 11:240

    Content type: Research

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  4. The identification of endometrial stem/progenitor cells in a high turnover rate tissue suggests that a well-orchestrated underlying network controls the behaviour of these stem cells. The thickness of the endo...

    Authors: Shan Xu, Rachel W. S. Chan, Tianqi Li, Ernest H. Y. Ng and William S. B. Yeung

    Citation: Stem Cell Research & Therapy 2020 11:239

    Content type: Research

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  5. Pluripotent stem cells present the ability to self-renew and undergo differentiation into any cell type building an organism. Importantly, a lot of evidence on embryonic stem cell (ESC) differentiation comes f...

    Authors: Anita Florkowska, Igor Meszka, Magdalena Zawada, Diana Legutko, Tomasz J. Proszynski, Katarzyna Janczyk-Ilach, Wladyslawa Streminska, Maria A. Ciemerych and Iwona Grabowska

    Citation: Stem Cell Research & Therapy 2020 11:238

    Content type: Research

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  6. Although it has been preclinically suggested that adipose tissue-derived mesenchymal stem cell (ADSC)-based therapy could effectively treat chronic liver diseases, the hepatic engraftment of ADSCs is still ext...

    Authors: Naishun Liao, Yingjun Shi, Yingchao Wang, Fangyu Liao, Bixing Zhao, Youshi Zheng, Yongyi Zeng, Xiaolong Liu and Jingfeng Liu

    Citation: Stem Cell Research & Therapy 2020 11:237

    Content type: Research

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  7. Dental pulp stem cells (DPSCs) have high proliferation and multi-differentiation capabilities that maintain their functionality after cryopreservation. In our previous study, we demonstrated that cryopreserved...

    Authors: Masaki Hata, Maiko Omi, Yasuko Kobayashi, Nobuhisa Nakamura, Megumi Miyabe, Mizuho Ito, Eriko Makino, Saki Kanada, Tomokazu Saiki, Tasuku Ohno, Yuka Imanishi, Tatsuhito Himeno, Hideki Kamiya, Jiro Nakamura, Shogo Ozawa, Ken Miyazawa…

    Citation: Stem Cell Research & Therapy 2020 11:236

    Content type: Research

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  8. We would like to thank for the interest for the article and comments in the response. We believe that cell therapy may offer a treatment for severe voice problems in patients with vocal fold scarring and MSC t...

    Authors: Stellan Hertegård and Katarina LeBlanc

    Citation: Stem Cell Research & Therapy 2020 11:235

    Content type: Commentary

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    The Commentary to this article has been published in Stem Cell Research & Therapy 2020 11:173

  9. Natural killer (NK) cells play a crucial role in host immunity by detecting cells that downregulate MHC class I presentation and upregulate stress ligands, as commonly seen in cancers. Current NK therapies usi...

    Authors: Keerthana Shankar, Christian M. Capitini and Krishanu Saha

    Citation: Stem Cell Research & Therapy 2020 11:234

    Content type: Review

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  10. Degeneration of smooth muscles in sphincters can cause debilitating diseases such as fecal incontinence. Skeletal muscle-derived cells have been effectively used in clinics for the regeneration of the skeletal...

    Authors: Marco Thurner, Martin Deutsch, Katrin Janke, Franka Messner, Christina Kreutzer, Stanislav Beyl, Sébastien Couillard-Després, Steffen Hering, Jakob Troppmair and Rainer Marksteiner

    Citation: Stem Cell Research & Therapy 2020 11:233

    Content type: Research

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  11. Preeclampsia (PE) is a frequently occurring pregnancy disorder in the placenta, which results in various maternal and fetal complications. The current study aims to evaluate the role of extracellular vesicles ...

    Authors: Jinhui Cui, Xinjuan Chen, Shuo Lin, Ling Li, Jianhui Fan, Hongying Hou and Ping Li

    Citation: Stem Cell Research & Therapy 2020 11:231

    Content type: Research

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  12. Proliferation and transdifferentiation of lung stem cells (LSCs) could promote lung injury repair. The distal airways of the lung are innervated by the vagus nerve. Vagal-alpha7 nicotinic acetylcholine recepto...

    Authors: Xiaoyan Chen, Caiqi Zhao, Cuiping Zhang, Qingmei Li, Jie Chen, Lianping Cheng, Jian Zhou, Xiao Su and Yuanlin Song

    Citation: Stem Cell Research & Therapy 2020 11:230

    Content type: Research

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  13. To investigate the therapeutic effect of human dental pulp stem cells (DPSCs) transfected with adenovirus expressing hepatocyte growth factor (HGF) in a mouse model of collagen-induced arthritis (CIA).

    Authors: Xiwen Dong, Fanxuan Kong, Chao Liu, Shiyun Dai, Yuning Zhang, Fengjun Xiao, Huan Zhang, Chu-Tse Wu and Hua Wang

    Citation: Stem Cell Research & Therapy 2020 11:229

    Content type: Research

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  14. The beneficial functions of bone marrow mesenchymal stem cells (BM-MSCs) decline with decreased cell survival, limiting their therapeutic efficacy for myocardial infarction (MI). Irisin, a novel myokine which ...

    Authors: Jingyu Deng, Ning Zhang, Yong Wang, Chao Yang, Yabin Wang, Chao Xin, Jinming Zhao, Zhitao Jin, Feng Cao and Zheng Zhang

    Citation: Stem Cell Research & Therapy 2020 11:228

    Content type: Research

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  15. Bone marrow mesenchymal stem cells (BMSCs) exhibit the capacity to self-renew and differentiate into multi-lineage cell types, including osteoblasts, which are crucial regulators of fracture healing. Thus, thi...

    Authors: Xueliang Zhang, Yongping Wang, Haiyan Zhao, Xingwen Han, Tong Zhao, Peng Qu, Guangjie Li and Wenji Wang

    Citation: Stem Cell Research & Therapy 2020 11:227

    Content type: Research

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  16. Adipose-derived mesenchymal stem cells (ADMSCs) have attracted widespread interest as cell-based tissue repair systems. To obtain adequate quantities of ADMSCs for therapeutic applications, extensive in vitro ...

    Authors: Qiliang Yin, Na Xu, Dongsheng Xu, Mingxin Dong, Xiumin Shi, Yan Wang, Zhuo Hao, Shuangshuang Zhu, Donghai Zhao, Haofan Jin and Wensen Liu

    Citation: Stem Cell Research & Therapy 2020 11:226

    Content type: Research

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  17. Acetaminophen (APAP) overdose is the common cause of acute liver failure (ALF) due to the oxidative damage of multiple cellular components. This study aimed to investigate whether plasma membrane vesicles (PMV...

    Authors: Mei-jia Lin, Shuang Li, Lu-jun Yang, Dan-yan Ye, Li-qun Xu, Xin Zhang, Ping-nan Sun and Chi-ju Wei

    Citation: Stem Cell Research & Therapy 2020 11:225

    Content type: Research

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  18. Myocardial infarction (MI) is a major cause of death worldwide. Although percutaneous coronary intervention and coronary artery bypass grafting can prolong life, cardiac damage persists. In particular, cardiom...

    Authors: Hao Cheng, Shufu Chang, Rende Xu, Lu Chen, Xiaoyue Song, Jian Wu, Juying Qian, Yunzeng Zou and Jianying Ma

    Citation: Stem Cell Research & Therapy 2020 11:224

    Content type: Research

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  19. Mesenchymal stem cell (MSC)-based therapy is currently considered to be an effective treatment strategy for diabetes and hepatic disorders, such as liver cirrhosis and non-alcoholic fatty liver disease. Exosom...

    Authors: Qin He, Lingshu Wang, Ruxing Zhao, Fei Yan, Sha Sha, Chen Cui, Jia Song, Huiqing Hu, Xinghong Guo, Mengmeng Yang, Yixin Cui, Yujing Sun, Zheng Sun, Fuqiang Liu, Ming Dong, Xinguo Hou…

    Citation: Stem Cell Research & Therapy 2020 11:223

    Content type: Research

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  20. Machado-Joseph disease is the most common autosomal dominant hereditary ataxia worldwide without effective treatment. Mesenchymal stem cells (MSCs) could slow the disease progression, but side effects limited ...

    Authors: Hua-Jing You, Shu-Bin Fang, Teng-Teng Wu, Hongyu Zhang, Yu-Kun Feng, Xue-Jiao Li, Hui-Hua Yang, Ge Li, Xun-Hua Li, Chao Wu, Qing-Ling Fu and Zhong Pei

    Citation: Stem Cell Research & Therapy 2020 11:222

    Content type: Research

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  21. Mesenchymal stem cells (MSCs) can improve limb perfusion and increase vessel density in a murine model of hindlimb ischemia. But low engraftment rate of those cells limited their therapeutic effect. Endothelia...

    Authors: Ziping Yao, Huihui Liu, Min Yang, Yun Bai, Bihui Zhang, Chengen Wang, Ziguang Yan, Guochen Niu, Yinghua Zou and Yuan Li

    Citation: Stem Cell Research & Therapy 2020 11:221

    Content type: Research

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  22. Restenosis is a serious problem in patients who have undergone percutaneous transluminal angioplasty. Endothelial injury resulting from surgery can lead to endothelial dysfunction and neointimal formation by i...

    Authors: Zhihui Liu, Chao Wu, Xinliang Zou, Weiming Shen, Jiacai Yang, Xiaorong Zhang, Xiaohong Hu, Haidong Wang, Yi Liao and Tao Jing

    Citation: Stem Cell Research & Therapy 2020 11:220

    Content type: Research

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  23. This study tested the optimal time point for left intra-carotid arterial (LICA) administration of circulatory-derived autologous endothelial progenitor cells (EPCs) for improving the outcome in rat after acute...

    Authors: Kun-Chen Lin, Han-Tan Chai, Kuan-Hung Chen, Pei-Hsun Sung, John Y. Chiang, Pei-Lin Shao, Chi-Ruei Huang, Yi-Chen Li, Sheung-Fat Ko and Hon-Kan Yip

    Citation: Stem Cell Research & Therapy 2020 11:219

    Content type: Research

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  24. Donation after circulatory death (DCD) liver grafts have a poor prognosis after transplantation. We investigated whether the outcome of DCD donor organs can be improved by heme oxygenase 1 (HO-1)-modified bone...

    Authors: Huan Cao, Liu Yang, Bin Hou, Dong Sun, Ling Lin, Hong-Li Song and Zhong-Yang Shen

    Citation: Stem Cell Research & Therapy 2020 11:218

    Content type: Research

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  25. A marked egg-induced CD4+ T cell programmed inflammation and subsequent hepatic fibrosis characterize the pathogenesis of schistosomiasis. Mesenchymal stem cell (MSC) has been extensively studied for the treatmen...

    Authors: Chao Liu, Yi-shu Zhang, Fang Chen, Xiao-ying Wu, Bei-bei Zhang, Zhong-dao Wu and Jun-xia Lei

    Citation: Stem Cell Research & Therapy 2020 11:217

    Content type: Research

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  26. In periodontal tissue engineering, periodontal ligament stem cells derived from patients with periodontitis (P-PDLSCs) are among the most promising and accessible stem cells for repairing disrupted alveolar bo...

    Authors: Han Li, Yuejia Deng, Minmin Tan, Ge Feng, Yunchun Kuang, Jie Li and Jinlin Song

    Citation: Stem Cell Research & Therapy 2020 11:215

    Content type: Research

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  27. Multiple studies have reported that mesenchymal stem cell (MSC) therapy has beneficial effects in experimental models of sepsis. However, this finding remains inconclusive. This study was performed to systemat...

    Authors: Xue-Yi Sun, Xian-Fei Ding, Huo-Yan Liang, Xiao-Juan Zhang, Shao-Hua Liu, Bing-Han, Xiao-Guang Duan and Tong-Wen Sun

    Citation: Stem Cell Research & Therapy 2020 11:214

    Content type: Research

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  28. Idiopathic pulmonary fibrosis is a chronic, progressive, and severe disease with a limited response to currently available therapies. Epithelial cell injury and failure of appropriate healing or regeneration a...

    Authors: Belén Alvarez-Palomo, Luis Ignacio Sanchez-Lopez, Yuben Moodley, Michael J. Edel and Anna Serrano-Mollar

    Citation: Stem Cell Research & Therapy 2020 11:213

    Content type: Research

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  29. The therapeutic effects of adipose-derived mesenchymal stem cell (ADSC) transplantation have been demonstrated in several models of central nervous system (CNS) injury and are thought to involve the modulation...

    Authors: Zhilai Zhou, Xiaobo Tian, Biling Mo, Huali Xu, Li Zhang, Lishan Huang, Shun Yao, Zixiang Huang, Yeyang Wang, Huan Xie, Liwei Xu and Hui Zhang

    Citation: Stem Cell Research & Therapy 2020 11:212

    Content type: Research

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  30. The differentiation of human mesenchymal stem cells (hMSCs) into osteoblasts (OBs) is a prerequisite for bone formation. However, little is known about the definitive surface markers for OBs during osteogenesis.

    Authors: Hyun Min Lee, Se-Ri Seo, Jeeseung Kim, Min Kyu Kim, Hyosun Seo, Kyoung Soo Kim, Young-Joo Jang and Chun Jeih Ryu

    Citation: Stem Cell Research & Therapy 2020 11:210

    Content type: Research

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  31. Noonan syndrome (NS) is a developmental disorder caused by mutations of Src homology 2 domain-containing protein tyrosine phosphatase 2 (SHP2). Although NS patients have diverse neurological manifestations, th...

    Authors: Younghee Ju, Jun Sung Park, Daejeong Kim, Bumsoo Kim, Jeong Ho Lee, Yoonkey Nam, Han-Wook Yoo, Beom Hee Lee and Yong-Mahn Han

    Citation: Stem Cell Research & Therapy 2020 11:209

    Content type: Research

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    The Correction to this article has been published in Stem Cell Research & Therapy 2020 11:282

  32. The novel coronavirus disease 2019 (COVID-19) has grown to be a global public health emergency since patients were first detected in Wuhan, China. Thus far, no specific drugs or vaccines are available to cure ...

    Authors: Yingxin Zhang, Jie Ding, Shaoda Ren, Weihua Wang, Yapei Yang, Shuangjing Li, Min Meng, Tiejun Wu, Daliang Liu, Suochen Tian, Hui Tian, Shuangfeng Chen and Changhui Zhou

    Citation: Stem Cell Research & Therapy 2020 11:207

    Content type: Short report

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  33. Exosomes derived from mesenchymal stem cells (MSC-exos) have been demonstrated with great potential in the treatment of multiple human diseases including acute kidney injury (AKI) by virtue of their intrinsic ...

    Authors: Jingyuan Cao, Bin Wang, Taotao Tang, Linli Lv, Zhaoying Ding, Zuolin Li, Ruoyu Hu, Qing Wei, Anran Shen, Yuqi Fu and Bicheng Liu

    Citation: Stem Cell Research & Therapy 2020 11:206

    Content type: Research

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  34. Mesenchymal stromal cell conditioned medium (MSC-CM) contains a cocktail of bioactive factors that act synergistically to induce therapeutic effects. This has been clearly demonstrated by in vivo applications ...

    Authors: K. Shoma Suresh, Samatha Bhat, Bharath Raja Guru, Manjunatha S. Muttigi and Raviraja N. Seetharam

    Citation: Stem Cell Research & Therapy 2020 11:205

    Content type: Research

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  35. Polydatin (PD), extracted from Polygonum cuspidatum, has shown potential therapeutic applications due to its antiosteoporotic and anti-inflammatory activities. Our previous study suggested that PD promotes the os...

    Authors: Ying-Shan Shen, Xiao-Jun Chen, Sha-Na Wuri, Fan Yang, Feng-Xiang Pang, Liang-Liang Xu, Wei He and Qiu-Shi Wei

    Citation: Stem Cell Research & Therapy 2020 11:204

    Content type: Research

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  36. Retinal and/or optic nerve injury is one of the leading causes of blindness due to retinal ganglion cell (RGC) degeneration. There have been extensive efforts to suppress this neurodegeneration. Various somati...

    Authors: Seyedeh-Zahra Seyedrazizadeh, Sara Poosti, Abdoreza Nazari, Mehdi Alikhani, Faezeh Shekari, Farzad Pakdel, Koorosh Shahpasand, Leila Satarian and Hossein Baharvand

    Citation: Stem Cell Research & Therapy 2020 11:203

    Content type: Research

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  37. Increasing evidence has revealed that long non-coding RNAs (lncRNAs) exert critical roles in biological mineralization. As a critical process for dentin formation, odontoblastic differentiation is regulated by...

    Authors: Jialin Zhong, Xinran Tu, Yuanyuan Kong, Liyang Guo, Baishun Li, Wenchao Zhong, Ying Cheng, Yiguo Jiang and Qianzhou Jiang

    Citation: Stem Cell Research & Therapy 2020 11:202

    Content type: Research

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  38. The original article omits an affiliation for authors, He Zhang and Dongjin Wang. The omitted affiliation can be viewed in this Correction article.

    Authors: Xumin Guan, Wanzi Xu, He Zhang, Qian Wang, Jiuyang Yu, Ruyi Zhang, Yamin Chen, Yunlong Xia, Jiaxian Wang and Dongjin Wang

    Citation: Stem Cell Research & Therapy 2020 11:201

    Content type: Correction

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    The original article was published in Stem Cell Research & Therapy 2020 11:73

  39. Accidentally removed parathyroid glands are still challenging in neck surgery, leading to hypoparathyroidism characterized with abnormally low levels of parathyroid hormone. Parathyroid auto-transplantation is...

    Authors: Qiuxia Cui, Dan Zhang, Deguang Kong, Jianing Tang, Xing Liao, Qian Yang, Jiangbo Ren, Yan Gong and Gaosong Wu

    Citation: Stem Cell Research & Therapy 2020 11:200

    Content type: Research

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  40. Osteoarthritis (OA) is a major cause of limb dysfunction, and distraction arthroplasty which generates intermittent hydrostatic pressure (IHP) is an effective approach for OA treatment. However, the result was...

    Authors: Hanhao Dai, Ran Chen, Chang Gui, Tianqi Tao, Yingbin Ge, Xilian Zhao, Ran Qin, Wangxiang Yao, Song Gu, Yiqiu Jiang and Jianchao Gui

    Citation: Stem Cell Research & Therapy 2020 11:199

    Content type: Research

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  41. Cutaneous wound healing represents a morphogenetic response to injury and is designed to restore anatomic and physiological function. Human bone marrow mesenchymal stem cell-derived exosomes (hBM-MSC-Ex) are a...

    Authors: Tiechao Jiang, Zhongyu Wang and Ji Sun

    Citation: Stem Cell Research & Therapy 2020 11:198

    Content type: Research

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  42. The inevitable side effects caused by lifelong immunosuppressive agents in kidney transplantation patients spurred the exploration of novel immunosuppressive strategies with definite curative effects and minim...

    Authors: Lingfei Zhao, Chenxia Hu, Fei Han, Fanghao Cai, Junni Wang and Jianghua Chen

    Citation: Stem Cell Research & Therapy 2020 11:197

    Content type: Review

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  43. Temperature is an important microenvironmental factor that functions epigenetically in normal embryonic development. However, the effect of hyperthermia in the stem cells is not fully understood. Oct4 is a tig...

    Authors: Mo-bin Cheng, Xue Wang, Yue Huang and Ye Zhang

    Citation: Stem Cell Research & Therapy 2020 11:195

    Content type: Letter

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  44. Recent studies suggest that circulating endothelial progenitor cells (EPCs) may influence the response to cardiac resynchronization therapy (CRT). The aim of this study was to evaluate the effect of CRT on EPC...

    Authors: Gonçalo Cristóvão, James Milner, Pedro Sousa, Miguel Ventura, João Cristóvão, Luís Elvas, Artur Paiva, Lino Gonçalves, Carlos Fontes Ribeiro and Natália António

    Citation: Stem Cell Research & Therapy 2020 11:194

    Content type: Research

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  45. RNA-binding protein, musashi1 (MSI1), is a main protein in asymmetric cell division of the sensory organ precursor cells, whereas its expression is reported to be upregulated in cancers. This protein is a crit...

    Authors: Mahboobeh Forouzanfar, Liana Lachinani, Kianoush Dormiani, Mohammad Hossein Nasr-Esfahani, Ali Osmay Gure and Kamran Ghaedi

    Citation: Stem Cell Research & Therapy 2020 11:193

    Content type: Review

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  46. Acute lung injury (ALI), an increasingly devastating human disorder, is characterized by a multitude of lung changes arising from a wide variety of lung injuries. Viral infection is the main cause of morbidity...

    Authors: Jiang Du, Han Li, Jie Lian, Xinxing Zhu, Liang Qiao and Juntang Lin

    Citation: Stem Cell Research & Therapy 2020 11:192

    Content type: Review

    Published on:

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