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Figure 4 | Stem Cell Research & Therapy

Figure 4

From: Comparative analysis of mesenchymal stem cell and embryonic tendon progenitor cell response to embryonic tendon biochemical and mechanical factors

Figure 4

Elastin (Eln) gene expression as a function of growth factor treatments and loading. Eln gene expression in mesenchymal stem cells (MSCs) and tendon progenitor cells (TPCs) on day (D)3 of treatment with combinations of mechanical loading (L), transforming growth factor (TGF)β2 (T), and fibroblast growth factor-4 (F), and normalized to D0. (A) MSCs significantly increased Eln with time in control culture and with loading. (B) TPCs significantly increased Eln with time in control culture and treatment with loading, TGFβ2, and TGFβ2 + loading. ↑ or ↓ indicates statistically significant up- or downregulation, respectively; *P < 0.05, **P < 0.01, ***P < 0.001.

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Stem Cell Research & Therapy

ISSN: 1757-6512