Figure 3
From: Mesenchymal stem cells-regulated Treg cells suppress colitis-associated colorectal cancer
MSCs protect mice against the development of DSS-induced colitis on day 33. Colons were excised for macroscopic observation (A) and assessment of colonic length (B). (C) The changes in body weight were calculated based on initial body weight. (D) The clinical disease score of colitis, which includes stool status, fecal blood, length of colon and weight loss, was used to evaluate the therapeutic effect of MSCs. (E) Colon sections from mice with different treatments were examined using H & E staining. (F) Histology scores were derived from microscopic analysis of longitudinal colon sections from each mouse. Values are expressed as means ± SEM. *P <0.05, or **P <0.01. DSS, dextran sulfate sodium; MSCs mesenchymal stem cells; SEM, standard error of the mean.