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Table 1 Criteria for histologic scoring of wound healing

From: Three-dimensional spheroid cell culture of umbilical cord tissue-derived mesenchymal stromal cells leads to enhanced paracrine induction of wound healing

Score

Re-epithelialization

Wound margins distance

Granulation tissue

Vascularization

0

<25% of re-epithelialization

Distant wound margins

Absent granulation

Presence of haemorrhage

1

25-50% of re-epithelialization

Distant wound margins by granulation tissue

<30% of granulation tissue

Presence of haemorrhage and capillaries

2

50-75% of re-epithelialization

Moderate distance between wound margins

Granulation in 30-60% of wound bed

Presence of many capillaries

3

>75% of re-epithelialization

Reduced distance between wound margins

>60% of granulation tissue

Presence of few capillaries

4

Complete re-epithelialization

Closed wound margins

Traces of granulation with presence of mature collagen fibres

No evident vascularization