Fig. 1

Pulp regeneration after ectopic tooth root transplantation in severe combined immunodeficiency mice. a, e, j Twenty-one days after transplantation of pulp CD31⁻ side population (SP) cells (Pulp SCs), (b, f, k) conditioned medium (CM) from pulp CD31⁻ SP cells (Pulp CM), (c, g, l) CM from bone marrow CD31⁻ SP cells (BM CM), and (d, h, m) CM from adipose CD31⁻ SP cells (AD CM). a-h Hematoxylin-and-eosin staining. i Ratio of regenerated area to root canal area on day 21. j-m Hoechst 33342 staining. n Cell density of the total regenerated area on day 21. Data are expressed as mean ± standard deviation of four determinations. *P < 0.05, **P < 0.01. Col. only, collagen only