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Fig. 8 | Stem Cell Research & Therapy

Fig. 8

From: CXCL14 and MCP1 are potent trophic factors associated with cell migration and angiogenesis leading to higher regenerative potential of dental pulp side population cells

Fig. 8

Trophic effects of CXCL14 and MCP1 compared with conditioned medium (CM) of pulp CD31− side population (SP) cells in vitro. a, b Effect of CXCL14 and MCP1 on migration (a) and its inhibition of anti-CXCL14 (a) or anti-MCP1 (b) (b) analyzed by TAXIScan-FL in (a) C2C12 and (b) human umbilical vein endothelial cells (HUVECs). c Angiogenic effect of MCP1 analyzed by immunocytochemistry with vascular endothelial (VE)-cadherin. Relative percentages of viable and apoptotic cells in the presence of 500 nM staurosporine analyzed by flow cytometry. Data are expressed as mean ± standard deviation of four determinations. *P < 0.05, **P < 0.01. CXCL14, Chemokine (C-X-C motif) ligand 14; MCP1, Monocyte chemotactic protein 1

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Stem Cell Research & Therapy

ISSN: 1757-6512