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Fig. 1 | Stem Cell Research & Therapy

Fig. 1

From: Induced pluripotent stem cell models of Zellweger spectrum disorder show impaired peroxisome assembly and cell type-specific lipid abnormalities

Fig. 1

Characterization of iPSCs derived from PBD-ZSD patient and healthy control donors. a Alkaline phosphatase (AP) staining and immunostaining for pluripotency markers in representative healthy control and patient iPSCs. b Immunostaining for cell populations derived from each of the three germ layers based on in vitro EB differentiation assays conducted on representative healthy control and patient iPSCs. c Teratomas derived from representative healthy control and patient iPSCs. Teratomas consisted of cell populations representative of all three germ layers. Scale bar = 50 μm. N neural rosettes; P pigment epithelium; C cartilage tissue; G glandular tissue

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Stem Cell Research & Therapy

ISSN: 1757-6512