Fig. 2

Relative expression of glycolytic genes in breast tumor versus benign tissue. The HypoxyGluMet array was employed on tumors (n = 15) and benign tissues (n = 11) to determine relative expression of a HIF-1 and HIF-1-dependent nonglycolytic genes, b HIF-1α-dependent glycolytic genes, and c HIF-1α-independent glycolytic genes. Average gene expression in tumor tissues is shown relative to average expression in benign tissues. Error bars represent the 95 % confidence interval. *p ≤0.05, **p ≤0.01