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Fig. 1 | Stem Cell Research & Therapy

Fig. 1

From: Assessment of bystander killing-mediated therapy of malignant brain tumors using a multimodal imaging approach

Fig. 1

In vitro validation of SPIO labeling of mOct4− BM-MAPCs. a ICP-OES data showed superior labeling of mOct4− BM-MAPCs using ihSPIO particles compared to labeling using Endorem® with unlabeled cells containing 1.3 ± 0.8 pg Fe/cell, ihSPIO-labeled mOct4- BM-MAPCs containing 15.9 ± 1.5 pg Fe/cell and Endorem®-labeled mOct4− BM-MAPCs 8.2 ± 0.6 pg Fe/cell. b An MRI phantom confirmed these results and showed the corresponding in vitro contrast generation caused by the presence of iron in the cells with enhanced signal decay corresponding to higher concentrations of iron/cell. c BLI using D-Luciferin as a substrate indicated no marked differences in cell viability between labeled and unlabeled cells. SMG 2 -mPEGSI second seed mediated growth-mPolyethylene glycol

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Stem Cell Research & Therapy

ISSN: 1757-6512