Fig. 2From: Native extracellular matrix preserves mesenchymal stem cell “stemness” and differentiation potential under serum-free culture conditionsCell number of primary BM-MSCs after culture in SFM or SCM for 14 days. Primary cultures of BM-MSCs were grown for 14 days on TCP, BM-ECM, or CELLstart™ in SCM or SFM. At harvest, cell number was determined by cell counting after staining with trypan blue. SCM was superior to SFM in promoting cell proliferation, but the overall trend observed with the three culture surfaces remained similar. *P < 0.05, significantly different from BM-ECM and CELLstart™; † P < 0.05, significantly different from BM-ECM. BM-ECM bone marrow-derived extracellular matrix, BM-MSC bone marrow-derived mesenchymal stem cell, SCM serum-containing media, SFM serum-free media, TCP tissue culture plasticBack to article page