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Fig. 1 | Stem Cell Research & Therapy

Fig. 1

From: Synergism of MSC-secreted HGF and VEGF in stabilising endothelial barrier function upon lipopolysaccharide stimulation via the Rac1 pathway

Fig. 1

The blocking effect of a anti-VEGF and b anti-HGF antibody on VEGF and HGF in MSC-CM. The results showed the actual levels of HGF and VEGF were 343 pg/ml and 99 pg/ml, respectively, in MSC-CM after 24 h of hypoxic culture. However, VEGF in MSC-CM was significantly blocked by 10 ng/ml or more anti-VEGF antibody (p < 0.01), while 100 ng/ml or more anti-HGF antibody significantly blocked HGF in MSC-CM (p < 0.01); n = 3, *p < 0.01 vs. 0 ng/ml. CM Conditioned medium, HGF Hepatocyte growth factor, MSC Mesenchymal stem cell, VEGF Vascular endothelial growth factor

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Stem Cell Research & Therapy

ISSN: 1757-6512