Fig. 5
From: Hyaluronan induces odontoblastic differentiation of dental pulp stem cells via CD44
HA induces phosphorylation of Smad1 on DPSCs. a DPSCs were treated with HA (10 μg/mL) over a time course of 5–360 min and then examined for phosphorylation of Smad1 by western blotting. b DPSCs were treated with HA (10 μg/mL) in the presence of DMH-1 for 30 min, and the inhibition of Smad1 phosphorylation was verified. c Following inhibition of Smad1 phosphorylation by DMH-1 treatment, DMP-1 expression was determined by western blotting. DMP-1 dentin matrix protein-1, HA hyaluronic acid