Fig. 4
Signal of DiD-haMSCs residing in the knee joint. a Detection of florescent imaging of representative rats in both nonsurgery and surgery groups over time. When DiD-haMSCs (2.5 × 106 cells) were injected into the right knee joint of the nonsurgery rats (top panel) and surgery rats (bottom panel), signals remained relatively stable in surgery joints and became undetectable after 70 days of injection while in the nonsurgery joints the signal diminished rather quickly at day 28. b Quantitative fluorescent intensity of the nonsurgery and surgery groups. Data show that the average (n = 2) fluorescent intensity appeared to fluctuate as time went on. Signals in the surgery group lasted much longer than in nonsurgery group