Fig. 1
From: High glucose suppresses embryonic stem cell differentiation into cardiomyocytes
Characteristics of parent E14 cells and the GR-E14 cells adapted to low glucose. a mRNA levels of pluripotent markers, OCT4, SOX2, KLF2, and LIN28, in parent E14 cells and E14 cells adapted to low glucose (GR-E14 cells). b Glut2 mRNA levels in GR-E14 and parent E14 cells. c mRNA levels of ectoderm marker SOX1, mesoderm marker T, and endoderm marker AFP in EBs. E14 E14 cells maintained under 25 mM glucose condition, EB embryoid body derived from E14 or GR-E14 cells, GR-E14 glucose-responsive E14 cell line, which was gradually adapted to 5 mM glucose medium from 25 mM glucose medium. All experiments were repeated three times (n = 3), the value was dedicated as mean ± SD. *Indicates significant difference compared with the other group(s)