From: Cardiotoxicity evaluation using human embryonic stem cells and induced pluripotent stem cell-derived cardiomyocytes
Drug
hESC-CMs
hiPSC-CMs
CI (μmol•L-1)
IC50/EC50 (μmol•L-1)
E-4031
0.01↑
0.02
0.1↓
0.04
Isoprenaline
1↓
0.03
Quinidine
100↓
2.18
13.97
Haloperidol
NO
0.14
10↓
5.17