Table 1 Characteristics of microcarriers tested and their respective seeding conditions per heMSC-microcarrier construct at day 0 of differentiation

 Diameter (μm)

147–248

141–211

100–400

130–380

 Matrix

Dextran

Dextran

Type I Collagen

Gelatin

 Charges/coating

Positively charged

Denatured collagen

–

–

 Porosity

Microporous

Microporous

Microporous

Macroporous

 Biodegradability

No

No

Yes

Yes

 Surface area (cm²/mg dry weight)

4.40

2.70

–

15.0

 Cell confluency

70%

70%

–

–

 Total cell number

10.1 × 10³

10.1 × 10³

–

–

 Microcarrier number

300

300

–

–

 Cell confluency

70%

70%

70%

70%

 Total cell number

10.1 × 10³

8.88 × 10³

8.88 × 10³

30.8 × 10³

 Microcarrier number

300

300

300

50