Skip to main content

Table 2 Different expression of genes at the 4-week follow-up in stem cell treated patients compared to control patients

From: Autologous bone marrow-derived cell transplantation in decompensated alcoholic liver disease: what is the impact on liver histology and gene expression patterns?

Accession number

Gene name

Affymetrix fold-expression

p value

Nanostring fold-expression

p value

Macrophages, inflammation, and chemotaxis

 NM_001040059, NM_001251

CD68

CD68 molecule

1.11

0.5874

5.19

0.0011

 NM_002993

CXCL6 (chemokine (C-X-C motif) ligand 6)

2.03

0.0327

3.42

0.2015

 NM_002985

CCL5 (chemokine (C-C motif) ligand 5)

1.53

0.0411

 NM_033439

IL33 (interleukin 33)

1.53

0.0336

 NM_000331, NM_001127380, NM_001178006, NM_030754, NM_199161

SAA-1 (serum amyloid A1)

1.73

0.0692

2.68

0.0455

 NM_001127380, NM_030754

SAA-2 (serum amyloid A2)

1.12

0.7873

3.11

0.0202

 NM_004887

CXCL14 (chemokine (C-X-C motif) ligand 14)

–2.13

0.0458

–6.32

0.1257

Liver regeneration and stem cells

 NM_000601, NM_001010931, NM_001010932, NM_001010933, NM_001010934

HGF (hepatocyte growth factor)

1.11

0.4825

7.50

0.0019

 NM_016639

TNFRSF12A (tumor necrosis factor receptor superfamily, member 12A)

1.15

0.4973

1.08

0.9551

 NM_003122

SPINK1 (serine peptidase inhibitor, Kazal type 1)

4.29

0.0446

19.95

0.0979

 NM_005556

CK7(keratin 7)

–1.11

0.7284

–3.38

0.3841

 NM_002276

CK19(keratin 19)

1.04

0.8957

–2.15

0.5533

 NM_002838, NM_080921, NM_080923

PTPRC (CD45) (protein tyrosine phosphatase, receptor type, C)

1.52

0.0473

8.98

0.0260

Fibrosis

 NM_000088

COL1A1

(collagen, type I, alpha 1)

1.38

0.1405

10.54

0.0101

Other

 NM_001142466, NM_133443

GPT2

–1.54

0.0201

 NM_001190463, NM_001902, NM_153742

–1.83

0.0365

 NM_001195728, NM_004171

SLC1A2 (solute carrier family 1 (glial high affinity glutamate transporter), member 2)

–2.22

0.0147

  1. Values shown in bold are significant at p < 0.05