Fig. 4

Effect of IL-3 on mRNA expression of CXCR4 in MSCs. BM-MSCs, AT-MSCs and GT-MSCs were treated with different concentrations of IL-3 for 24 hours and fold change in mRNA expression of CXCR4 was analyzed using real-time PCR (a). CXCR4 mRNA expression in MSCs incubated with IL-3 (100 ng/ml) was analyzed after 12, 18 and 24 hours (b). Data shown as mean ± SEM of three independent experiments. *p ≤ 0.05, **p ≤ 0.01 and ***p ≤ 0.001 vs control groups. AT adipose tissue, BM bone marrow, CTRL control, CXCR4 chemokine (C-X-C motif) receptor 4, GT gingival tissue, IL-3 interleukin-3, MSC mesenchymal stem cell