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Table 3 Effects of BMC transplantation over time

From: Effects of timing on intracoronary autologous bone marrow-derived cell transplantation in acute myocardial infarction: a meta-analysis of randomized controlled trials

 

No. of RCTs

Difference in mean (95% CI)

P value

LV ejection fraction

 Follow up < 6 months

7

1.45 [0.54 to 2.36]

0.002

 Follow up > 6, < 12 months

13

0.83 [–1.85 to 3.51]

0.54

 Follow up ≥ 12 months

14

3.58 [1.55 to5.61]

0.0006

LV end-diastolic indexes

 Follow up < 6 months

6

–4.76 [–8.19 to –1.33]

0.006

 Follow up > 6, < 12 months

7

–0.60 [–3.38 to 2.18]

0.67

 Follow up ≥ 12 months

13

–4.00 [–8.13 to 0.13]

0.06

LV end-systolic indexes

 Follow up < 6 months

5

–4.29 [–11.51 to 2.92]

0.24

 Follow up > 6, < 12 months

5

0.51 [–1.92 to 2.95]

0.68

 Follow up ≥ 12 months

13

–7.07 [–11.99 to –2.14]

0.005

  1. RCTs randomized controlled trials, 95% CI 95% confidence interval