Table 3 Diastolic function parameters compared between the study groups, mean ± SD; median (Q3–Q1)
|  | Control (n = 25) | Intervention (n = 20) | Repeated intervention (n = 20) | P value |
|---|---|---|---|---|
E baseline | 0.63 ± 0.24 0.56 (0.64–0.46) | 0.57 ± 0.19 0.53 (0.82–0.37) | 0.64 ± 0.24 0.58 (0.63–0.46) | 0.511 |
E Final | 0.73 ± 0.21 0.62 (0.91–0.57) | 0.58 ± 0.19 0.54 (0.8–0.41) | 0.58 ± 0.17 0.56 (0.61–0.51) | 0.002 |
A baseline | 0.64 ± 0.15 0.66 (0.77–0.57) | 0.64 ± 0.16 0.56 (0.85–0.51) | 0.68 ± 0.14 0.75 (0.77–0.58) | 0.649 |
A Final | 0.68 ± 0.2 0.66 (0.72–0.59) | 0.62 ± 0.08 0.66 (0.67–0.53) | 0.62 ± 0.07 0.65 (0.67–0.57) | 0.386 |
e′ baseline | 0.05 ± 0.01 0.05 (0.06–0.04) | 0.08 ± 0.03 0.08 (0.11–0.05) | 0.05 ± 0.01 0.05 (0.06–0.04) | 0.001 |
e′ final | 0.6 ± 1.89 0.06 (0.08–0.05) | 1.81 ± 3.08 0.08 (5.27–0.07) | 1.53 ± 2.9 0.08 (0.09–0.06) | 0.001 |
EA-ratio baseline | 0.95 ± 0.31 0.8 (1.1–0.73) | 0.88 ± 0.17 0.96 (1.04–0.66) | 0.93 ± 0.33 0.78 (1.1–0.72) | 0.779 |
E/A-ratio final | 1.19 ± 0.67 0.97 (1.2–0.88) | 0.96 ± 0.31 0.95 (1.03–0.62) | 0.95 ± 0.29 0.97 (1.1–0.76) | 0.6 |
E/e′-ratio baseline | 13.15 ± 6.58 11.7 (15–7.7) | 7.56 ± 2.53 7.5 (10.6–4.6) | 12.65 ± 5.91 11.9 (15–7.6) |  < 0.001 |
E/e′-ratio final | 12.04 ± 6.34 11.3 (17.5–8.2) | 5.95 ± 4.27 6.36 (10.4–1.1) | 6.33 ± 4.2 8.5 (10.4–3.2) | 0.002 |