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Fig. 4 | Stem Cell Research & Therapy

Fig. 4

From: Mesenchymal stem/stromal cells from human pluripotent stem cell-derived brain organoid enhance the ex vivo expansion and maintenance of hematopoietic stem/progenitor cells

Fig. 4

Transcriptome analysis for hematopoietic cells and MSCs. A Heatmaps showing genes related to ECM that were differentially expressed in H1-hESC, hiPSC, H1-MSCs, hiPSC-MSCs, and UC-MSCs. B Heatmaps showing genes related to HSC maintenance were differentially expressed in H1-MSCs, hiPSC-MSCs, and UC-MSCs. C Venn diagram showing the number of common and distinct upregulated genes in the CD34+ cells cocultured with H1-MSCs, hiPSC-MSCs, and UC-MSCs compared with that without stromal cells. D, E GO term analysis for common and distinct upregulated genes in the CD34+ cells cocultured with H1-MSCs, hiPSC-MSCs, and UC-MSCs compared with that without stromal cells. F HSC, HPC, GMP, and MEP signature gene expression in CD34+ cells cocultured with and without H1MSCs, hiPSC-MSCs, and UC-MSCs

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Stem Cell Research & Therapy

ISSN: 1757-6512