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Fig. 4 | Stem Cell Research & Therapy

Fig. 4

From: Good manufacturing practice production of human corneal limbus-derived stromal stem cells and in vitro quality screening for therapeutic inhibition of corneal scarring

Fig. 4

A Continuous growth kinetics of donor CSSC cultured in a pair-wise comparison of laboratory-based and GMP conditions. Both cell batches from donor corneas 610, 617 and 618 exhibited gradual propagation. B Similar expression levels of stem cell markers in GMP and JM-H raised CSSC. Both of them had significantly lower expression of keratocan and lumican, when compared to quiescent stromal keratocytes. SF—stromal fibroblasts were used as negative control for the reduced expression of keratocan and lumican. * P < 0.05, compared to quiescent keratocytes; one-way ANOVA, nonparametric

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