Fig. 2

Pulp regeneration after complete disinfection with levofloxacin and nanobubbles in model A. A–C, E, F Hematoxylin and eosin staining. A, B Regenerated pulp tissue. C, D Odontoblastic cells (arrow) lining to newly formed osteodentin/tubular dentin (OD) along with the dentin. D Immunohistological staining for Dspp. E Osteodentin (OD) was regenerated in the coronal part of the root canal. F Periapical tissue healing. Alveolar bone (AB). G Blood vessels stained by BS-1 lectin (arrows). H Neuronal process stained by PGP 9.5 (arrows). I–L Modification of the Brown and Brenn Gram staining. I Root canal surface of dentin (De). J Deep inside dentin (De). K Cementum (Ce). L Periapical tissue (Pa)